S13C11aP9a-1: This is an example of subcutaneous angiolymphoid hyperplasia with eosinophilia; the lesion is tumoral and circumscribed. There is a peripheral condensation of fibrous tissue. At the bottom of the
field, there is a cap of lymphoid tissue along the surface of the condensed fibrous tissue. Internally, the lesion is lobulated. The band of tissue identified by green arrows is the remnant of a muscular vessel; its
lumen has been replaced by lesional tissue in a lobular array.
S13C11aP9a-2: Some of the vessels of the lobules are lined by plump, acidophilic cells; red arrows identify two cells, each with a cytoplasmic vesicle. These two cells qualify as angioblasts. The loose lymphoid
infiltrates in the supporting fibrous matrix show a sprinkling of eosinophils.
S13C11aP9a-3: The vessel to the left of the center of the field shows cells that are typical of angiolymphoid hyperplasia with eosinophilia. The cellular lymphoid tissue to the right shows a rich admixture of
eosinophils. In addition, there is a rich plexus of vessels of a type characterized as post-capillary venules (vessels with “high” endothelial cells). Vessels showing these features are ideally suited for the egress
of cellular components from the lumens of the vessels into the tissue.
S13C11aP9a-4: The vessel of S13C11aP9a-3 is seen at higher magnification (subcutaneous, tumoral angiolymphoid hyperplasia with eosinophilia).
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